2018-2022

NIH R01 MH112543 / MPI: Yen, Birmaher

The purpose of this multi-site longitudinal study is to examine the course and outcome of bipolar youth as they age into early and middle adulthood. Using this data and data from other studies, we seek to build risk calculators to help predict illness outcomes.

2018-2021

NIH R34 AT009886 (NCT03831360) / MPI Yen, Uebelacker

The purpose of this project is to modify yoga intervention for depressed adolescents and pilot the intervention. We will then conduct a randomized clinical trial comparing yoga to group Cognitive Behavioral Therapy - for adolescents with MDD.

2017-2019

NIH R21 MH113183 / MPI: Yen, Mereish

The purpose of this study is to examine the factors that lead LGBT youth to have higher rates of suicidal and nonsuicidal self-injurious behaviors. Specific factors include the role of emotion regulation, low self-esteem, interpersonal rejection sensitivity, and stresses and experiences unique to LGBT populations (e.g., minority stress).

2016-2019

Privately funded / PI Yen

The purpose of this study is to develop a multimodal group based intervention for depressed young adults to increase attention to positive affect. Delivery of skills occurs in in-person group sessions as well daily remote delivery via SMS.

2013-2016

NIH R34 MH101272 / PI Yen 

This treatment development project aimed to develop a personalized multi-modal intervention to increase positive affect and decrease suicidal ideation in adolescents admitted to the inpatient psychiatric unit for suicide risk. Skills and psychoeducation were delivered in-person sessions and reinforced through text-messaging.

2011-2018

NIH 5R01 MH059691 / MPI Yen, Keller

The purpose of this multisite, long-term prospective naturalistic study of 400 children, adolescents, and young adults with bipolar disorder was to investigate how the phenomenology, treatment responsiveness, and course of bipolar disorder are influenced by the developmental transitions from childhood through young adulthood.

2011-2014

NIH R34 MH090147 / MPI

This treatment development grant adapted the Coping Long Term with Attempted Suicide program (CLASP) for use in adolescents (CLASP-A). The aim was to examine the feasibility and acceptability of CLASP-A delivered to adolescent admitted due to suicide risk, during their inpatient hospital admission.

2005-2010

NIH K23 MH069904 / PI

This career-development award provided the PI with training in research with suicidal adolescents. The research study examined prospective predictors of suicidal behaviors over six-months of follow-up, in adolescents hospitalized due to suicide risk.

1999-2000 

Executive Committee on Research Award, Department of Psychiatry and Human Behavior, Brown Medical School / PI 

This grant examined emotion regulation profiles in women with borderline personality to identify characteristics associated with an over-regulated profile vs. an under-regulated profile.

1995-1996

Ford Foundation: Social Science Research Council / PI 

This grant examined how depressive symptoms are manifested in a clinical sample in China, a student sample in China, and a student sample in the United States, to elucidate the roles of stigma, culture, and acculturation in symptom manifestation and reporting.